Nifedipine ointment and chronic anal fissure
Acta Med Iran. Sep-Oct;48(5) The effect of topical nifedipine in treatment of chronic anal fissure. Golfam F(1), Golfam P, Khalaj A, Sayed Mortaz SS.
Is topical nifedipine effective for chronic anal fissures?
This extremely safe, well tolerated, and effective treatment should provide family physicians with a reliable nonsurgical method for treating chronic anal fissures.
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Description:A comparison of injections of botulinum toxin and topical nitroglycerin ointment for the treatment of chronic anal fissure. Reduction of hypertonocity is a special treatment for fissure healing. Patients in the nifedipine group showed significant healing and relief from pain compared with patients in the control group. Headaches occurred in First-line therapies include a diet high in fiber, approximately 25 to 35 g per day. Recurrence of symptoms occurred in four of healed patients in the nifedipine group and three patients in the control group in two months.